Postdoctoral positions are now available in the laboratory of Dr. Yilun Liu at the Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope. Dr. Liu’s research focus relates to (1) dissecting the mechanism by which cells prevent the formation of endogenous DNA breaks as a consequence of unresolved collision between a replication fork and a transcription machinery or a transcription-induced R-loop; (2) developing pharmaceutical mechanisms for cancer therapy by targeting enzymes important for resolving R-loops or transcription-replication collisions to enhance DNA break formation as well as factors important for the BRCA2 and PARP-dependent repair pathways to keep these DNA breaks unrepaired; and (3) targeting mitochondrial DNA as signaling molecule in immune response and cancer therapy.
Basic education, experience and skills required for consideration:
- A Ph.D. degree in life or biomedical sciences, or a related discipline is required.
- Experience in biochemistry and/or cell biology is preferred
- For more information on Dr. Yilun Liu’s research please visit, here.
- Dr. Liu’s group has published in journals, including Nature Communications, Cell Reports, EMBO Journal and PNAS. A full list of publications can be found here.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.