The Department of Defense (DoD) is offering post-bachelor’s internships at Walter Reed Army Institute of Research (WRAIR).
What will I be doing?
As an ORISE participant, you will join a community of scientists in drug discovery research performed by the WRAIR Experimental Therapeutics Branch.
You will gain experience learning under the research team on established in vitro drug toxicity and efficacy screening assays against Plasmodium parasites and other assays addressing ET Branch/Department of Drug Discovery goals for antimicrobial (including malaria, bacteria, and/or viruses) drug discovery and development as needed. You will also have the opportunity to learn assay-related tasks, conduct data/results analysis, generate research reports and manuscripts for publication, along with opportunities for intra- and extramural presentations.
Why should I apply?
Under the guidance of a mentor, you will gain hands-on experience to complement your education and support your academic and professional goals. Along the way, you will engage in activities and research in several areas. These include, but are not limited to:
- Conduct phenotypic-based drug screening and target-based enzymatic assays for anti-hypnozoite drug discovery and development
- Maintain microbial cultures or infected mosquitos for use in the in vitro assays
- Develop, optimize, validate, and perform high throughput in vitro assays for various therapeutic areas
- Prepare validation packets
- Make detailed observations, document results, perform data analysis/management using internal CoreLIMS system
- Analyze/summarize experimental data for reports, presentations, posters and publications
- Attend/present at relevant national scientific conferences if required
- Maintain a safe workplace ensuring that you are aware of appropriate safety and occupational health rules and regulations
Where will I be located?
Silver Spring, Maryland
What is the anticipated start date?
The Walter Reed Army Institute of Research is ready to make appointments immediately. Exact start dates will be determined at the time of selection and in coordination with the selected candidate. Applications are reviewed on an ongoing basis and internships or fellowships will be filled as qualified candidates are identified.
What is the appointment length?
This appointment is a twelve month research appointment, with the possibility to be renewed for additional research periods. Appointments may be extended depending on funding availability, project assignment, program rules, and availability of the participant.
What are the benefits?
You will receive a stipend to be determined by Walter Reed Army Institute of Research. Stipends are typically based on a participant’s academic standing, discipline, experience, and research facility location. Other benefits may include the following:
- Health Insurance Supplement (Participants are eligible to purchase health insurance through ORISE)
- Relocation Allowance
- Training and Travel Allowance
The Walter Reed Army Institute of Research (WRAIR) aims to conduct biomedical research that is responsive to U.S. Department of Defense and U.S. Army requirements. WRAIR conducts basic science, applied science, and animal and human subjects research to deliver lifesaving products including knowledge, technology and medical material that sustain the combat effectiveness of the Warfighter. Areas of focus include tropical infectious diseases and HIV, medical care on the battlefield and post-traumatic stress disorders. For more information about the WRAIR, please visit www.wrair.army.mil.
This program, administered by Oak Ridge Associated Universities (ORAU) through its contract with the U.S. Department of Energy (DOE) to manage the Oak Ridge Institute for Science and Education (ORISE), was established through an interagency agreement between DOE and DoD. Participants do not enter into an employee/employer relationship with ORISE, ORAU, DoD or any other office or agency. Instead, you will be affiliated with ORISE for the administration of the appointment through the ORISE appointment letter and Terms of Appointment. Proof of health insurance is required for participation in this program. Health insurance can be obtained through ORISE. For more information, visit the ORISE Research Participation Program at the U.S. Department of Defense.
The qualified candidate will have a Bachelor’s degree in Biological or Biomedical Sciences. Degree must have been received within 60 months of the appointment start date.
Highly competitive candidates will have:
- Excellent written and verbal communication skills
- Background in microbiology/parasitology/cell biology
- Publication record in microbial and hepatoxicity (malaria preferred) research and drug discovery.
- Experience in small molecule drug discovery, Plasmodium pre-erythrocytic biology, and experience with in vitro cell culture (preferably primary hepatocytes and hepatoma cell lines).
- Experience working with mosquitoes, salivary gland dissections, malaria liver-stage related assays, and microscopy is an advantage.
- High self-motivation, strong critical-thinking skills, and exemplary communication and collaboration skills.
- Degree: Bachelor’s Degree received within the last 60 months