*Applications will be reviewed on a rolling-basis.
A research opportunity is currently available in the Chronic Viral Diseases Branch (CVDB) within the Division of High Consequence Pathogens and Pathology (DHCPP) of the National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) at the Centers for Disease Control and Prevention (CDC) located in Atlanta, Georgia.
Under the guidance of a mentor, the selected participant will join laboratory staff in projects related to next generation sequencing and other technologies for developing cost-effective, practical and advanced genotyping methods for Human Papillomavirus (HPV). As part of this goal, the participant will plan and perform hands-on experiments with a variety of molecular methods that includes next generation sequencing incorporating target enrichment approaches as applied to a wide variety of samples including formalin-fixed paraffin embedded tissues. Training environment will provide opportunity to interact and learn with a team of biomedical researchers and computational biologists. Specific activities may include:
- Conduct laboratory studies to identify cost-effective, practical and advanced HPV genotyping platforms that include target enrichment methods for HPV
- Perform deep sequencing of HPV using Illumina and Ion-Torrent platforms iand n collaboration with CDC Scientific Core-Facility
- Evaluation of Illumina and Ion-Torrents equence data following recommended quality control metrics and perform initial data processing using Illumina and/or other recommended software
- Participate in evaluating performance characteristics and applications of the next generation genotyping test for HPV surveillance studies
- Conduct literature survey and monitor advances in next generation technologies as applicable to microbial genomics
- Recording and maintaining hard copy and electronic copies of laboratory notebooks detailing experiments and results, and submitting technical reports and project summaries of activites performed as requested
- Performing quality control and safety procedures necessary for the performance of laboratory protocols involved in working with biohazard materials
- Participate in laboratory quality management activities as assigned
- Attending weekly Branch meetings that address current scientific activities of the Branch
Anticipated Appointment Start Date: September 6, 2021 (start date is flexible)
This program, administered by ORAU through its contract with the U.S. Department of Energy to manage the Oak Ridge Institute for Science and Education, was established through an interagency agreement between DOE and CDC. The initial appointment can be up to one year, but may be renewed upon recommendation of CDC contingent on the availability of funds. The participant will receive a monthly stipend commensurate with educational level and experience. Proof of health insurance is required for participation in this program. The appointment is full-time at CDC in the Atlanta, Georgia, area. Participants do not become employees of CDC, DOE or the program administrator, and there are no employment-related benefits.
If you have questions, send an email to ORISE.CDC.NCEZID@orau.org. Please include the reference code for this opportunity in your email.