*Applications will be reviewed on a rolling-basis.
A research opportunity is currently available in the Viral Vaccine Preventable Diseases Branch (VVPDB), Division of Viral Diseases (DVD) of the National Center for Immunization and Respiratory Diseases (NCIRD) at the Centers for Disease Control and Prevention (CDC) located in Atlanta, Georgia.
DVD is responsible for surveillance for many viruses associated with vaccine preventable and non-vaccine preventable viral diseases. VVPDB is a Global Specialized Laboratory within the WHO Measles and Rubella Laboratory Network. Understanding the prevalence of measles and rubella antibodies in a population can help verify vaccination coverage rates and identify populations that may be at risk of measles or rubella virus transmission and outbreaks. VVPDB has developed a multiplex bead assay (MBA) to evaluate population seroprevalence. This assay is already in use for a large-scale serosurvey with more studies pending. At the same time, assay development continues, with the goal of integrating the assay with other MBAs.
To help accomplish these goals, the selected fellow will join the measles team within VVPDB. Under the guidance of a mentor, opportunities may include:
- Modifying assay conditions to harmonize with MBA protocols used by other CDC programs
- Performing quality control of bead lots and data analysis of quality control data
- Testing large panels of sera by MBA to generate data for serosurveys
- Evaluating antigens for bead coupling to integrate testing for immunity against additional pathogens
- Developing a method to measure the antigen content of commercially available antigen preparations
The results of this fellowship will provide VVPDB with an optimized MBA that will be used to generate serosurveillance data for countries in the measles and rubella laboratory network. The selected fellow will collaborate with subject matter experts and team members who have established the MBA in VVPDB. The fellow may provide technical and experimental support for transferring the assay to other countries.
Anticipated Appointment Start Date: September 2021; start date is flexible
This program, administered by ORAU through its contract with the U.S. Department of Energy to manage the Oak Ridge Institute for Science and Education, was established through an interagency agreement between DOE and CDC. The initial appointment can be up to one year, but may be renewed upon recommendation of CDC contingent on the availability of funds. The participant will receive a monthly stipend commensurate with educational level and experience. Proof of health insurance is required for participation in this program. The appointment is full-time at CDC in the Atlanta, Georgia, area. Participants do not become employees of CDC, DOE or the program administrator, and there are no employment-related benefits.
If you have questions, send an email to ORISE.CDC.NCIRD@orau.org. Please include the reference code for this opportunity in your email.