*Applications will be reviewed on a rolling-basis.
A research opportunity is currently available at the U.S. Food and Drug Administration (FDA), Center for Drug Evaluation and Research (CDER), Office of Translational Sciences/Office of Clinical Pharmacology located in Silver Spring, Maryland.
Under the guidance of a mentor the participant may be involved in the development of (quantitative) structure-activity relationship ((Q)SAR) models to predict blood-brain barrier (BBB) permeability and various efflux transporter interactions. The participant will be part of a highly collaborative, multidisciplinary environment. Specifically, in collaboration with a mentor, the participant may be involved in one or more of the following aspects of the project: developing and applying data-mining tools; reviewing, extracting, and harmonizing data from the literature; constructing and enhancing training databases for modeling purposes; developing, validating and optimizing (Q)SAR models; constructing chemical structure-linked knowledge bases with enhanced search capabilities. This research project represents an excellent scientific development opportunity in a visible, high priority program.
This program, administered by ORAU through its contract with the U.S. Department of Energy to manage the Oak Ridge Institute for Science and Education, was established through an interagency agreement between DOE and FDA. The initial appointment is for one year, but may be renewed upon recommendation of FDA contingent on the availability of funds. The participant will receive a monthly stipend commensurate with educational level and experience. Proof of health insurance is required for participation in this program. The appointment is full-time at FDA in the Silver Spring, Maryland, area. Participants do not become employees of FDA, DOE or the program administrator, and there are no employment-related benefits.
If you have questions, send an email to ORISE.FDA.CDER@orau.org. Please include the reference code for this opportunity in your email.