The Cancer Stem Cell Dynamics laboratory of Dirk Loeffler is seeking exceptionally motivated and ambitious candidates for a Postdoctoral Position, starting Jan. 1st, 2024, or the earliest date thereafter. If you are curious, creative, and goal-oriented with a keen interest in science, technology, and data this is the right position for you!
We study the genetic and epigenetic changes in blood stem and progenitor cells during hematopoietic diseases and aging. The ideal candidate is curious, self-motivated, independent, hard-working, and has excellent communication and interpersonal skills. Experiences in cell and molecular biology or related fields and a strong desire to learn new techniques are prerequisites. A background in hematology is preferred but not required and candidates from a wide variety of fields with a genuine interest in stem cells and the origins of cancer are encouraged to apply.
You will have the opportunity to work with a young and talented interdisciplinary team to decipher the molecular mechanisms regulating normal and mutant blood stem cell behaviors and decisions. Our laboratory uses molecular and cell biological tools, mouse models, next-generation sequencing, high-resolution 3D microscopy, gene-editing, bioinformatics, and novel long-term continuous quantitative live-cell imaging to understand the molecular mechanisms of hematological diseases at the single-cell level to develop novel therapies.
Responsibilities:
The selected person will conduct projects and perform experiments independently and as part of a team, maintain efficient laboratory operations, learn new techniques, and assist in training other laboratory personnel as summarized below.
- Design and conduct laboratory research experiments.
- Document, interpret, and present the results of experiments.
- Learn, implement, and troubleshoot new laboratory techniques & technologies.
- Collect, compile, and analyze data; maintain detailed records.
- Training of less experienced research staff and students
- Reading literature, contributing your own ideas, and showing initiative
- Preparation of data and texts for publication
In this position, you will gain extensive experience and training in various cell and molecular biology techniques, mouse models, flow cytometry, genome editing, confocal microscopy, time-lapse imaging, single-cell analysis, bioinformatics, data presentation, and interpretation. We strongly support the career development of all lab members through opportunities to publish in high-impact journals, obtain grants, and present work at academic conferences.
For more information about our lab and recent publications visit:
https://www.stjude.org/research/labs/loeffler-lab.html
Minimum Education:
Ph.D. Documented scientific productivity in terms of scientific publication!